SUMMARY The apothecary occupied a liminal position in early modern society between profit and healing. Finding ways to distance their public image from trade was a common problem for apothecaries across Europe. This article uses the case of a Bolognese apothecary, Filippo Pastarino, to address the question of how early modern apothecaries chose to represent themselves to political authorities and to the wider public. ‘Mercy’, alongside ‘craft’, was a pillar of apothecaries’ social identity. By contrast, no matter how central financial (...) transactions (‘money’) were to their activity, apothecaries did not want to be perceived as merchants. Thus, the assistance and advice apothecaries provided to patients and customers resulted as central aspects of their social role. In this context, Bolognese apothecaries aimed to defend their current status, which had been challenged by naturalist Ulysses Aldrovandi, city authorities and local monasteries. However, Pastarino's claims can also be seen as antecedents to the self-legitimizing strategy that seventeenth-century artisans deployed when faced with the need to enhance their new status as natural philosophers. The present study attributes a name, a date of birth and a shop to Filippo Pastarino, revising previous interpretations. More broadly, by focusing on how these artisans defended their position in the city it enriches our understanding of the self-representation of apothecaries. (shrink)

Market inefficiency is a latent concept, and it is difficult to be measured by means of a single indicator. In this paper, following both the adaptive market hypothesis and the fractal market hypothesis, we develop a new time-varying measure of stock market inefficiency. The proposed measure, called composite efficiency index, is estimated as the synthesis of the most common efficiency measures such as the returns’ autocorrelation, liquidity, volatility, and a new measure based on the Hurst exponent, called the Hurst efficiency (...) index. To empirically validate the indicator, we compare different European stock markets in terms of efficiency over time. (shrink)

We use the example of the introduction of the anti-smoking legislation to model the relationship between the cultural make-up, in terms of values, of societies and the acceptance of and compliance with norms. We present two agent-based simulations and discuss the challenge of modeling sanctions and their relation to values and culture.

Introduction: Motor evoked potentials (MEPs) to transcranial magnetic stimulation are known to be susceptible to several sources of variability. However, conflicting evidences on individual characteristics in relatively small sample sizes have been reported. We investigated the effect of age, height, and sex on MEPs of the motor cortex and spinal roots in a large cohort. Methods: A total of 587 subjects clinically and neuroradiologically intact were included. MEPs were recorded during mild tonic contraction through a circular coil applied over the (...) “hot spot” of the first dorsal interosseous and tibialis anterior muscles, bilaterally. Central motor conduction time (CMCT) was estimated as the difference between MEP cortical latency and the peripheral motor conduction time by cervical or lumbar magnetic stimulation. Peak-to-peak MEP amplitude to cortical stimulation and right-to-left difference of each parameter were also measured. Results: After Bonferroni correction, general linear (multiple) regression analysis showed that both MEP cortical latency and peripheral motor conduction time at four limbs positively correlated with age and height. At lower limbs, an independent effect of sex on the same measures was also observed (with females showing smaller values than males). CMCT correlated with both age (negatively) and height (positively) when analyzed by a single regression; however, with a multiple regression analysis this significance disappeared, due to the correction for the multicollinearity within the dataset. Conclusions: Physical individual features need to be considered for a more accurate and meaningful MEPs interpretation. Both in clinical practice and in research setting, patients and controls should be matched for age, height, and sex. (shrink)

La città, risultato della storia, della cultura e della civiltà, si presenta a noi, a un primo impatto, come un’esaltazione dell’edificare in un gioco delle forme e dei volumi, o come una glorificazione dell’architettura; in un secondo momento viene percepita anche come un segno delle comunità e dell’appartenenza di cui le forme sono il riflesso. Si profila, a ben ragionare sul suo significato, dall’antichità alla modernità, un composito fare umano, il disegno straordinario dell’azione collettiva e dei singoli, l’effetto di un’arte (...) dello spazio esteso. Esso interagisce con ciò che si chiama l’arte del paesaggio, perché propone elementi della cura, dell’immaginazione e della progettazione, i segni della fantasia e le creazioni della necessità. Allo stesso modo di un’attività dove l’uomo è creatore di coltivazioni, si può dire infatti che esista un’arte della città come prodotto delle comunità e dei singoli, degli architetti e degli artisti, dei progettisti e dei semplici lavoratori, dei cittadini e dei loro rappresentanti politici: risultato di uno sforzo ideale e civile, ma anche di un concreto, sfaccettato manifestarsi delle tecniche nello spazio, modellato anche, volta a volta, da quel certo gruppo sociale o dalle ideologie. (shrink)